Physician

Internal Medicine

Dr. Tin Sein, MD

Sein is an expert in the field of Internal Medicine. Tin Sein is a published doctor. He has 37 papers published. The most current publication "Synergistic interaction of the triple combination of amphotericin B, ciprofloxacin, and polymorphonuclear neutrophils against Aspergillus fumigatus."

Publications

Fibronectin activates matrix metalloproteinase-9 secretion via the MEK1-MAPK and the PI3K-Akt pathways in ovarian cancer cells.
A role for FAK in the Concanavalin A-dependent secretion of matrix metalloproteinase-2 and -9.
Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1.
Synergistic interaction of the triple combination of amphotericin B, ciprofloxacin, and polymorphonuclear neutrophils against Aspergillus fumigatus.
Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis.
Effects of immunomodulatory and organism-associated molecules on the permeability of an in vitro blood-brain barrier model to amphotericin B and fluconazole.
Combination therapy in treatment of experimental pulmonary aspergillosis: in vitro and in vivo correlations of the concentration- and dose- dependent interactions betw...
Comparative pharmacodynamic interaction analysis between ciprofloxacin, moxifloxacin and levofloxacin and antifungal agents against Candida albicans and Aspergillus fu...
Detection of a molecular biomarker for zygomycetes by quantitative PCR assays of plasma, bronchoalveolar lavage, and lung tissue in a rabbit model of experimental pulm...
Galactomannan antigenemia in pediatric oncology patients with invasive aspergillosis.
In vitro activity of CAY-1, a saponin from Capsicum frutescens, against Microsporum and Trichophyton species.
Isobolographic analysis of pharmacodynamic interactions between antifungal agents and ciprofloxacin against Candida albicans and Aspergillus fumigatus.
Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei.
Comparative in vitro pharmacodynamics of caspofungin, micafungin, and anidulafungin against germinated and nongerminated Aspergillus conidia.
Zygomycosis in children: a systematic review and analysis of reported cases.
Pathogenesis of Aspergillus fumigatus and the kinetics of galactomannan in an in vitro model of early invasive pulmonary aspergillosis: implications for antifungal the...
Use of high inoculum for early metabolic signalling and rapid susceptibility testing of Aspergillus species.
Concentration-dependent effects of caspofungin on the metabolic activity of Aspergillus species.
Compartmentalized intrapulmonary pharmacokinetics of amphotericin B and its lipid formulations.
Triazole-polyene antagonism in experimental invasive pulmonary aspergillosis: in vitro and in vivo correlation.
Relationship between metabolism and biomass of medically important zygomycetes.
Multidimensional volumetric imaging of pulmonary infiltrates for measuring therapeutic response to antifungal therapy in experimental invasive pulmonary aspergillosis.
Rapid susceptibility testing of medically important zygomycetes by XTT assay.
Use of quantitative real-time PCR to study the kinetics of extracellular DNA released from Candida albicans, with implications for diagnosis of invasive Candidiasis.
Epidemiology and outcome of zygomycosis: a review of 929 reported cases.
Expression of genes encoding innate host defense molecules in normal human monocytes in response to Candida albicans.
Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis ...
Saliva affects the antifungal activity of exogenously added histatin 3 towards Candida albicans.
Detection of galactomannan antigenemia in patients receiving piperacillin-tazobactam and correlations between in vitro, in vivo, and clinical properties of the drug-an...
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resist...
Experimental pulmonary aspergillosis due to Aspergillus terreus: pathogenesis and treatment of an emerging fungal pathogen resistant to amphotericin B.
Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin.
Macrophage colony-stimulating factor enhances phagocytosis and oxidative burst of mononuclear phagocytes against Penicillium marneffei conidia.
Amphotericin B formulations exert additive antifungal activity in combination with pulmonary alveolar macrophages and polymorphonuclear leukocytes against Aspergillus ...
Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistent...
Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relat...

Doctors Specialties

Geriatric Medicine
Internal Medicine

Accepted Insurances

Education

University Institute of Medicine 1

Hospital

Michael E. DeBakey Veterans Affairs Medical Center

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