Assistant Professor, Medicine, Perelman School of Medicine
Internal Medicine
Dr. Robert J. Pignolo, MD
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Doctor Robert J. Pignolo, MD works in the field of Internal Medicine. He over the years received 2 awards: "Regional Top Doctor" and "CMS Meaningful Use Stage 1 Certification". Robert Pignolo is a published doctor. He has 49 papers published. The most current publication "Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation." Robert Pignolo accepts all Medicare patients.
Publications
- The immunological contribution to heterotopic ossification disorders.
- Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism.
- Conservation of pro-longevity genes among mammals.
- Teriparatide as a Systemic Treatment for Lower Extremity Non-Union Fractures: A Case Series.
- Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.
- R-spondin 1 promotes vibration-induced bone formation in mouse models of osteoporosis.
- From mysteries to medicines: drug development for fibrodysplasia ossificans progressive.
- Fibrodysplasia ossificans progressiva: diagnosis, management, and therapeutic horizons.
- Brief report: long-term functional engraftment of mesenchymal progenitor cells in a mouse model of accelerated aging.
- Boning-up on aortic valve calcification.
- Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.
- Paternally inherited gsα mutation impairs adipogenesis and potentiates a lean phenotype in vivo.
- Bone histomorphometry using free and commonly available software.
- Fibrodysplasia Ossificans Progressiva: Clinical and Genetic Aspects.
- Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis.
- Role for Circulating Osteogenic Precursor Cells in Aortic Valvular Disease.
- Heterozygous inactivation of Gnas in adipose-derived mesenchymal progenitor cells enhances osteoblast differentiation and promotes heterotopic ossification.
- Substance P signaling mediates BMP dependent heterotopic ossification.
- Circulating osteogenic cells: Implications for injury, repair, and regeneration.
- Viewing FOP through rosi-colored glasses.
- Circulating osteogenic precursor cells.
- Circulating osteogenic precursor cells in heterotopic bone formation.
- Morphogen receptor genes and metamorphogenes: skeleton keys to metamorphosis.
- Hematopoietic stem-cell contribution to ectopic skeletogenesis.
- v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.
- Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes.
- Putative role for EPC-1/PEDF in the G0 growth arrest of human diploid fibroblasts.
- Progressive osseous heteroplasia: diagnosis, treatment, and prognosis.
- Effects of donor age on the expression of a marker of replicative senescence (EPC-1) in human dermal fibroblasts.
- Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation.
- Senescent WI-38 fibroblasts overexpress LPC-1, a putative transmembrane shock protein.
- The pathway of cell senescence: WI-38 cells arrest in late G1 and are unable to traverse the cell cycle from a true G0 state.
- Development and age-associated differences in electron transport potential and consequences for oxidant generation.
- Cloning of the human twist gene: its expression is retained in adult mesodermally-derived tissues.
- Molecular markers of senescence in fibroblast-like cultures.
- Expression of hydrogen peroxide and glutathione metabolizing enzymes in human skin fibroblasts derived from donors of different ages.
- Molecular biology of aging.
- Alterations in contact and density-dependent arrest state in senescent WI-38 cells.
- Analysis of EPC-1 growth state-dependent expression, specificity, and conservation of related sequences.
- Alterations in the molecular response to DNA damage during cellular aging of cultured fibroblasts: reduced AP-1 activation and collagenase gene expression.
- Identification of proteins differentially expressed in quiescent and proliferatively senescent fibroblast cultures.
- Expression and regulation of superoxide dismutase activity in human skin fibroblasts from donors of different ages.
- Diagnostic and mutational spectrum of progressive osseous heteroplasia (POH) and other forms of GNAS-based heterotopic ossification.
- Exploring human/animal intersections: converging lines of evidence in comparative models of aging.
- A new era for fibrodysplasia ossificans progressiva: a druggable target for the second skeleton.
- Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis.
- Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP).
- The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling.
Schools
Medical College of Pennsylvania
Doctors Specialties
- Geriatric Medicine
- Internal Medicine
Accepted Insurances
Awards
- Regional Top Doctor
- CMS Meaningful Use Stage 1 Certification
Education
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University of Pennsylvania Health System -
Drexel University - Hahnemann University Hospital
Hospital
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Hospital of the University of Pennsylvania -
Penn Presbyterian Medical Center
Drug Facts
| NPI NUMBER | 1558302315 | |
| NPPES Provider LastName | PIGNOLO | |
| NPPES Provider FirstName | ROBERT | |
| NPPES Provider ZIPCode | 191042612 | |
| NPPES Provider State | PA | |
| Specialty Description | Geriatric Medicine | |
| Total Claim Count | 58.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1558302315 |
| Last Name Of The Provider | PIGNOLO |
| First Name Of The Provider | ROBERT |
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