Professor, Pathology and Laboratory Medicine, Perelman School of Medicine
Pathology
Dr. Mariusz A. Wasik, MD
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Mariusz A. Wasik practices Pathology. He studied medicine at Wroclaw Medical University. Mariusz A. Wasik, MD is a published MD. He has 101 papers published. The most current publication "The effect of salbutamol treatment on the cellular immunity of the offspring of pregnant mice: spleen cell activity." Dr. Mariusz A. Wasik accepts Medicare payments and is listed with Medicare.gov.
Publications
- Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse Leukemias expressing oncogenic ABL1 kinases.
- PRMT5 Is Required for Lymphomagenesis Triggered by Multiple Oncogenic Drivers.
- Combined B12 and folate deficiency presenting as an aggressive Hematologic malignancy.
- Cutaneous T Cell Lymphoma Expresses Immunosuppressive CD80 (B7-1) Cell Surface Protein in a STAT5-Dependent Manner.
- Development of Lymphomas Containing Epstein-Barr Virus After Therapy With Hyper-CVAD Regimen.
- Malignant Transformation of CD4+ T Lymphocytes Mediated by Oncogenic Kinase NPM/ALK Recapitulates IL-2-Induced Cell Signaling and Gene Expression Reprogramming.
- Intravascular Large B Cell Lymphoma Presenting as a Thyroid Mass.
- Targeting CD30 in Malignant Tissues: Challenges in Detection and Clinical Applications.
- ALK Inhibitor PF02341066 (Crizotinib) Increases Sensitivity to Radiation in Non-Small Cell Lung Cancer Expressing EML4-ALK.
- Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell Lymphoma.
- Prediction and Early Detection of Response by NMR Spectroscopy and Imaging.
- The role of cytokine signaling in the pathogenesis of cutaneous T-cell Lymphoma.
- Diagnostic microRNA profiling in cutaneous T-cell Lymphoma (CTCL).
- IFN-α primes T- and NK-Cells for IL-15-mediated signaling and cytotoxicity.
- Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS.
- Malignant Cutaneous T-Cell Lymphoma Cells Express IL-17 Utilizing the Jak3/Stat3 Signaling Pathway.
- Epstein-Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-Lymphoma cells through up-regulation of survivin.
- Simultaneous Inhibition of mTOR-Containing Complex 1 (mTORC1) and MNK Induces Apoptosis of Cutaneous T-Cell Lymphoma (CTCL) Cells.
- Deficient SOCS3 and SHP-1 expression in psoriatic T Cells.
- Lack of TNFalpha expression protects anaplastic Lymphoma kinase-positive T-cell Lymphoma (ALK+ TCL) cells from apoptosis.
- Activation of mTORC1 signaling pathway in AIDS-related Lymphomas.
- Ectopic expression of B-lymphoid kinase in cutaneous T-cell Lymphoma.
- Anaplastic Lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches.
- Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).
- Successful treatment of relapsed lymphomatoid granulomatosis With bexarotene.
- Gamma c-signaling cytokines induce a regulatory T Cell phenotype in malignant CD4+ T lymphocytes.
- IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes.
- Differential effects of interleukin-2 and interleukin-15 versus interleukin-21 on CD4+ cutaneous T-cell Lymphoma cells.
- IL-21 enhances antitumor responses Without stimulating proliferation of malignant T cells of patients With Sézary syndrome.
- Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication.
- STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression.
- Nonmalignant T cells stimulate growth of T-cell Lymphoma cells in the presence of bacterial toxins.
- PU.1 activates transcription of SHP-1 gene in hematopoietic Cells.
- Loss of SHP-1 tyrosine phosphatase expression correlates With the advanced stages of cutaneous T-cell lymphoma.
- Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative Disorders.
- Peroxisome proliferator-activated receptor gamma promotes lymphocyte survival through its actions on Cellular metabolic activities.
- Mantle cell Lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity.
- STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes.
- Nucleophosmin/anaplastic Lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3.
- Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.
- Id1 transcription inhibitor-matrix metalloproteinase 9 axis enhances invasiveness of the breakpoint cluster region/abelson tyrosine kinase-transformed Leukemia cells.
- Posttransplantation lymphoproliferative disease With features of lymphomatoid granulomatosis in a lung transplant patient.
- Inhibition of ALK enzymatic activity in T-cell Lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3.
- Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extraCellular s...
- STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.
- Treatment of primary Epstein-Barr virus infection in patients With X-linked lymphoproliferative disease using B-cell-directed therapy.
- Progressive epidermotropic CD8+/CD4- primary cutaneous CD30+ lymphoproliferative disorder in a patient With sarcoidosis.
- Complete remission in advanced blastic NK-cell lymphoma/Leukemia in elderly patients using the hyper-CVAD regimen.
- Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of Cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses.
- Detection of protein tyrosine-kinase (PTK) gene expression pattern in normal and malignant T lymphocytes by combined PTK-specific polymerase chain reaction and paralle...
- Natural killer-like T-cell lymphoma of the small intestine With a distinct immunophenotype and lack of association With gluten-sensitive enteropathy.
- Expression of anaplastic Lymphoma kinase in non-Hodgkin's Lymphomas and other malignant neoplasms. Biological, diagnostic, and clinical implications.
- SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell Lymphoma cells.
- Expression of SHP-1 phosphatase indicates post-germinal center Cell derivation of B-Cell posttransplant lymphoproliferative disorders.
- Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated leukemogenesis.
- Posttransplantation lymphoproliferative disorder of the paranasal sinuses mimicking invasive fungal sinusitis: case report.
- Multilevel dysregulation of STAT3 activation in anaplastic Lymphoma kinase-positive T/null-cell Lymphoma.
- Frequency of distribution of inflammatory cytokines IL-1, IL-6 and TNF-alpha gene polymorphism in patients With obstructive sleep apnea.
- Nitrogranulogen enhances IL-1 production but decreases Cellular sensitivity to this cytokine.
- B Cell dysfunction in renal allograft recipients.
- The role of cow''s milk protein intolerance in steroid-resistant nephrotic syndrome.
- Thymus and lymph node Cell CD4(+) and CD8(+) marker expression and their angiogenic activity of offspring of salbutamol-treated pregnant C3H mice.
- [Myelogenous system cells'' activity in the bone marrow in children with Acute leukemia remission].
- Granulocyte chemiluminescence activity, antibody production and percentage of CD4(+) and CD8(+) lymphocytes in peripheral blood of offspring of salbutamol-treated preg...
- Freeze-dried thymocytes as antigen source for production of antithymocyte sera.
- An optimal assay of human B Cell proliferation in vitro.
- [Selected cellular immunity parameters in patients With Lesniowski-Crohn disease].
- [Functional state of the lymphocytes of the peripheral blood in uveal and retinal Diseases. Preliminary report].
- [Cellular cytotoxicity in the studies of immunosuppressive activity of drugs].
- The effect of salbutamol treatment on the Cellular immunity of the offspring of pregnant mice: spleen Cell activity.
- [Problems of phenotypic diagnosis of Acute leukemia in children].
- Potentiation of the anti-tumour effects of Photofrin-based photodynamic therapy by localized treatment With G-CSF.
- The influence of low-power helium-neon laser irradiation on function of selected peripheral blood Cells.
- Effect of FK 506 on B-Cell responses.
- New strategies of heparin treatment used to prolong allograft survival.
- Studies on in vitro production of Paul-Bunnell antibodies.
- [Assesment of the selected T and B lymphocyte subsets in children With newly diagnosed insulin-dependent diabetes mellitus].
- [Targeted immunotherapy against interleukin 2 receptors (IL-2R)--an attempt at synthesis].
- Induction of macrophage membrane interleukin 1 expression by T-Cell dependent and T-Cell independent pathways is inhibited by cyclosporin A.
- Class II antigens and interleukin 2 expression in renal allograft recipients.
- Release of cytokines and soluble cytokine receptors after intravenous anti-D treatment in children with Chronic thrombocytopenic purpura.
- Expression of CD20 on Acute lymphoblastic leukemia cells in children.
- Expression of CD152 (CTLA-4) in children With autoimmune thyroiditis and +49 A/G polymorphism of exon 1 of the CTLA-4 gene.
- [The immunobiological effects of nitrogranulogen. I. Summarizing the results of the immunological studies to date].
- Natural killer cell activity of peripheral blood mononuclear cells from patients With various forms of lupus erythematosus.
- Natural killer cell activity of peripheral blood mononuclear cells from patients With various forms of systemic scleroderma.
- Effect of FK506 and cyclosporine on primary and secondary skin allograft survival in mice.
- Cytomegalovirus pseudotumor presenting as bowel obstruction in a patient With acquired immunodeficiency syndrome.
- Effect of FK506 versus cyclosporine on human natural and antibody-dependent cytotoxicity reactions in vitro.
- Changes in the phagocytic cells in children treated With continuous ambulatory peritoneal dialysis.
- Large granular lymphocyte lymphocytosis With neutropenia: a case report.
- Study of antibody dependent Cellular cytotoxicity (ADCC). III. Preliminary findings concerning the influence of immunosuppressive drugs.
- [Classification of human T lymphocytes by monoclonal antibodies - its theoretical and clinical aspects].
- Altered expression of immune surface markers in children With recurrent infections of respiratory tract.
- Effect of FK-506 and cyclosporine on human T and B lymphoproliferative responses.
- Nasal T-cell Lymphoma and the lethal midline granuloma syndrome.
- Diagnostic and prognostic value of antibody-dependent Cellular cytotoxicity and lectin-induced Cellular cytotoxicity tests for renal graft rejection.
- COX-2 is a novel target in therapy of Mycosis fungoides.
- The comparison of susceptibility of two target Cells (HuRBC and L1210) to antibody dependent lymphocyte cytotoxicity.
- The comparison of antibody-dependent (ADCC) and lectin-induced (LICC) cytotoxic activities of human blood lymphocytes in healthy and Diseased subjects.
Schools
We Wroclawiu Im Piastow Slaskich Academy of Medicine
Mallory Institute Path
Beth Israel Hospital
Conditions Treated
- Acute Leukemia
- Anemia
- Chronic Myeloid Leukemia (CML)
- Cryoglobulinemia
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Doctors Specialties
- Hematology
- Hematopathology
- Pathology
Accepted Insurances
Education
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Beth Israel Deaconess Medical Center -
Boston University Medical Center -
Wroclaw Medical University
Hospital
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Hospital of the University of Pennsylvania -
Pennsylvania Hospital -
Penn Presbyterian Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1023053576 |
| Last Name Of The Provider | WASIK |
| First Name Of The Provider | MARIUSZ |
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